Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of upper and lower motor neurons, associated with frontotemporal dementia (FTD) in about 14% of incident cases. We assessed the frequency of the recently identified C9orf72 repeat expansion in familial and app...

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Detalles Bibliográficos
Autores principales: Byrne, Susan, Elamin, Marwa, Bede, Peter, Shatunov, Aleksey, Walsh, Cathal, Corr, Bernie, Heverin, Mark, Jordan, Norah, Kenna, Kevin, Lynch, Catherine, McLaughlin, Russell L, Iyer, Parameswaran Mahadeva, O'Brien, Caoimhe, Phukan, Julie, Wynne, Brona, Bokde, Arun L, Bradley, Daniel G, Pender, Niall, Al-Chalabi, Ammar, Hardiman, Orla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Pub. Group 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315021/
https://www.ncbi.nlm.nih.gov/pubmed/22305801
http://dx.doi.org/10.1016/S1474-4422(12)70014-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315021/
https://www.ncbi.nlm.nih.gov/pubmed/22305801
http://dx.doi.org/10.1016/S1474-4422(12)70014-5

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