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Hobbes: optimized gram-based methods for efficient read alignment

Recent advances in sequencing technology have enabled the rapid generation of billions of bases at relatively low cost. A crucial first step in many sequencing applications is to map those reads to a reference genome. However, when the reference genome is large, finding accurate mappings poses a sig...

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Detalles Bibliográficos
Autores principales: Ahmadi, Athena, Behm, Alexander, Honnalli, Nagesh, Li, Chen, Weng, Lingjie, Xie, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315303/
https://www.ncbi.nlm.nih.gov/pubmed/22199254
http://dx.doi.org/10.1093/nar/gkr1246