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Recognition of methylated DNA through methyl-CpG binding domain proteins

DNA methylation is a key regulatory control route in epigenetics, involving gene silencing and chromosome inactivation. It has been recognized that methyl-CpG binding domain (MBD) proteins play an important role in interpreting the genetic information encoded by methylated DNA (mDNA). Although the f...

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Detalles Bibliográficos
Autores principales: Zou, Xueqing, Ma, Wen, Solov'yov, Ilia A., Chipot, Christophe, Schulten, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315304/
https://www.ncbi.nlm.nih.gov/pubmed/22110028
http://dx.doi.org/10.1093/nar/gkr1057