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Promiscuous DNA synthesis by human DNA polymerase θ

The biological role of human DNA polymerase θ (POLQ) is not yet clearly defined, but it has been proposed to participate in several cellular processes based on its translesion synthesis capabilities. POLQ is a low-fidelity polymerase capable of efficient bypass of blocking lesions such as abasic sit...

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Detalles Bibliográficos
Autores principales: Hogg, Matthew, Sauer-Eriksson, A. Elisabeth, Johansson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315306/
https://www.ncbi.nlm.nih.gov/pubmed/22135286
http://dx.doi.org/10.1093/nar/gkr1102