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Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs

Spliceosomes remove introns from primary gene transcripts. They assemble de novo on each intron through a series of steps that involve the incorporation of five snRNP particles and multiple non-snRNP proteins. In mammals, all the intermediate complexes have been characterized on one transcript (MINX...

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Detalles Bibliográficos
Autores principales: Makarov, Evgeny M., Owen, Nicholas, Bottrill, Andrew, Makarova, Olga V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315330/
https://www.ncbi.nlm.nih.gov/pubmed/22110043
http://dx.doi.org/10.1093/nar/gkr1056