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Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs
Spliceosomes remove introns from primary gene transcripts. They assemble de novo on each intron through a series of steps that involve the incorporation of five snRNP particles and multiple non-snRNP proteins. In mammals, all the intermediate complexes have been characterized on one transcript (MINX...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315330/ https://www.ncbi.nlm.nih.gov/pubmed/22110043 http://dx.doi.org/10.1093/nar/gkr1056 |