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Collective Dynamics Differentiates Functional Divergence in Protein Evolution
Protein evolution is most commonly studied by analyzing related protein sequences and generating ancestral sequences through Bayesian and Maximum Likelihood methods, and/or by resurrecting ancestral proteins in the lab and performing ligand binding studies to determine function. Structural and dynam...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315450/ https://www.ncbi.nlm.nih.gov/pubmed/22479170 http://dx.doi.org/10.1371/journal.pcbi.1002428 |