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Intronic Cis-Regulatory Modules Mediate Tissue-Specific and Microbial Control of angptl4/fiaf Transcription

The intestinal microbiota enhances dietary energy harvest leading to increased fat storage in adipose tissues. This effect is caused in part by the microbial suppression of intestinal epithelial expression of a circulating inhibitor of lipoprotein lipase called Angiopoietin-like 4 (Angptl4/Fiaf). To...

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Detalles Bibliográficos
Autores principales: Camp, J. Gray, Jazwa, Amelia L., Trent, Chad M., Rawls, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315460/
https://www.ncbi.nlm.nih.gov/pubmed/22479192
http://dx.doi.org/10.1371/journal.pgen.1002585