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Balanced Codon Usage Optimizes Eukaryotic Translational Efficiency

Cellular efficiency in protein translation is an important fitness determinant in rapidly growing organisms. It is widely believed that synonymous codons are translated with unequal speeds and that translational efficiency is maximized by the exclusive use of rapidly translated codons. Here we estim...

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Detalles Bibliográficos
Autores principales: Qian, Wenfeng, Yang, Jian-Rong, Pearson, Nathaniel M., Maclean, Calum, Zhang, Jianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315465/
https://www.ncbi.nlm.nih.gov/pubmed/22479199
http://dx.doi.org/10.1371/journal.pgen.1002603