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Balanced Codon Usage Optimizes Eukaryotic Translational Efficiency
Cellular efficiency in protein translation is an important fitness determinant in rapidly growing organisms. It is widely believed that synonymous codons are translated with unequal speeds and that translational efficiency is maximized by the exclusive use of rapidly translated codons. Here we estim...
Autores principales: | Qian, Wenfeng, Yang, Jian-Rong, Pearson, Nathaniel M., Maclean, Calum, Zhang, Jianzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315465/ https://www.ncbi.nlm.nih.gov/pubmed/22479199 http://dx.doi.org/10.1371/journal.pgen.1002603 |
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