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The Atypical Calpains: Evolutionary Analyses and Roles in Caenorhabditis elegans Cellular Degeneration

The calpains are physiologically important Ca(2+)-activated regulatory proteases, which are divided into typical or atypical sub-families based on constituent domains. Both sub-families are present in mammals, but our understanding of calpain function is based primarily on typical sub-family members...

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Detalles Bibliográficos
Autores principales: Joyce, Peter I., Satija, Rahul, Chen, Maozi, Kuwabara, Patricia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315469/
https://www.ncbi.nlm.nih.gov/pubmed/22479198
http://dx.doi.org/10.1371/journal.pgen.1002602