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Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein
The principal virulence determinant of Mycobacterium tuberculosis (Mtb), the ESX-1 protein secretion system, is positively controlled at the transcriptional level by EspR. Depletion of EspR reportedly affects a small number of genes, both positively or negatively, including a key ESX-1 component, th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315491/ https://www.ncbi.nlm.nih.gov/pubmed/22479184 http://dx.doi.org/10.1371/journal.ppat.1002621 |