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Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein

The principal virulence determinant of Mycobacterium tuberculosis (Mtb), the ESX-1 protein secretion system, is positively controlled at the transcriptional level by EspR. Depletion of EspR reportedly affects a small number of genes, both positively or negatively, including a key ESX-1 component, th...

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Detalles Bibliográficos
Autores principales:	Blasco, Benjamin, Chen, Jeffrey M., Hartkoorn, Ruben, Sala, Claudia, Uplekar, Swapna, Rougemont, Jacques, Pojer, Florence, Cole, Stewart T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315491/ https://www.ncbi.nlm.nih.gov/pubmed/22479184 http://dx.doi.org/10.1371/journal.ppat.1002621

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