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Kinetics of Inclusion Body Formation and Its Correlation with the Characteristics of Protein Aggregates in Escherichia coli

The objective of the research was to understand the structural determinants governing protein aggregation into inclusion bodies during expression of recombinant proteins in Escherichia coli. Recombinant human growth hormone (hGH) and asparaginase were expressed as inclusion bodies in E.coli and the...

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Detalles Bibliográficos
Autores principales: Upadhyay, Arun K., Murmu, Aruna, Singh, Anupam, Panda, Amulya K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315509/
https://www.ncbi.nlm.nih.gov/pubmed/22479486
http://dx.doi.org/10.1371/journal.pone.0033951