GC-Content Normalization for RNA-Seq Data

BACKGROUND: Transcriptome sequencing (RNA-Seq) has become the assay of choice for high-throughput studies of gene expression. However, as is the case with microarrays, major technology-related artifacts and biases affect the resulting expression measures. Normalization is therefore essential to ensu...

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Detalles Bibliográficos
Autores principales: Risso, Davide, Schwartz, Katja, Sherlock, Gavin, Dudoit, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315510/
https://www.ncbi.nlm.nih.gov/pubmed/22177264
http://dx.doi.org/10.1186/1471-2105-12-480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315510/
https://www.ncbi.nlm.nih.gov/pubmed/22177264
http://dx.doi.org/10.1186/1471-2105-12-480

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