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GC-Content Normalization for RNA-Seq Data
BACKGROUND: Transcriptome sequencing (RNA-Seq) has become the assay of choice for high-throughput studies of gene expression. However, as is the case with microarrays, major technology-related artifacts and biases affect the resulting expression measures. Normalization is therefore essential to ensu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315510/ https://www.ncbi.nlm.nih.gov/pubmed/22177264 http://dx.doi.org/10.1186/1471-2105-12-480 |