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Identification of Novel Mt-Guab2 Inhibitor Series Active against M. tuberculosis

Tuberculosis (TB) remains a leading cause of mortality worldwide. With the emergence of multidrug resistant TB, extensively drug resistant TB and HIV-associated TB it is imperative that new drug targets be identified. The potential of Mycobacterium tuberculosis inosine monophosphate dehydrogenase (I...

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Detalles Bibliográficos
Autores principales: Usha, Veeraraghavan, Hobrath, Judith V., Gurcha, Sudagar S., Reynolds, Robert C., Besra, Gurdyal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315515/
https://www.ncbi.nlm.nih.gov/pubmed/22479467
http://dx.doi.org/10.1371/journal.pone.0033886