Derlin-1 Deficiency Is Embryonic Lethal, Derlin-3 Deficiency Appears Normal, and Herp Deficiency Is Intolerant to Glucose Load and Ischemia in Mice

Accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) causes a cellular condition called ER stress. To overcome ER stress, unfolded proteins are eliminated by an ER-associated degradation (ERAD) system. To explore the physiological requirements for ERAD-related membrane pr...

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Detalles Bibliográficos
Autores principales: Eura, Yuka, Yanamoto, Hiroji, Arai, Yuji, Okuda, Tomohiko, Miyata, Toshiyuki, Kokame, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315519/
https://www.ncbi.nlm.nih.gov/pubmed/22479592
http://dx.doi.org/10.1371/journal.pone.0034298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315519/
https://www.ncbi.nlm.nih.gov/pubmed/22479592
http://dx.doi.org/10.1371/journal.pone.0034298

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