Hedgehog Signaling in Tumor Cells Facilitates Osteoblast-Enhanced Osteolytic Metastases

The remodeling process in bone yields numerous cytokines and chemokines that mediate crosstalk between osteoblasts and osteoclasts and also serve to attract and support metastatic tumor cells. The metastatic tumor cells disturb the equilibrium in bone that manifests as skeletal complications. The He...

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Detalles Bibliográficos
Autores principales: Das, Shamik, Tucker, J. Allan, Khullar, Shikha, Samant, Rajeev S., Shevde, Lalita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315536/
https://www.ncbi.nlm.nih.gov/pubmed/22479615
http://dx.doi.org/10.1371/journal.pone.0034374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315536/
https://www.ncbi.nlm.nih.gov/pubmed/22479615
http://dx.doi.org/10.1371/journal.pone.0034374

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