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Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as Hypertension Susceptibility Genes in Han Chinese with a Genome-Wide Gene-Based Association Study

Hypertension is a complex disorder with high prevalence rates all over the world. We conducted the first genome-wide gene-based association scan for hypertension in a Han Chinese population. By analyzing genome-wide single-nucleotide-polymorphism data of 400 matched pairs of young-onset hypertensive...

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Detalles Bibliográficos
Autores principales: Yang, Hsin-Chou, Liang, Yu-Jen, Chen, Jaw-Wen, Chiang, Kuang-Mao, Chung, Chia-Min, Ho, Hung-Yun, Ting, Chih-Tai, Lin, Tsung-Hsien, Sheu, Sheng-Hsiung, Tsai, Wei-Chuan, Chen, Jyh-Hong, Leu, Hsin-Bang, Yin, Wei-Hsian, Chiu, Ting-Yu, Chern, Ching-Iuan, Lin, Shing-Jong, Tomlinson, Brian, Guo, Youling, Sham, Pak C., Cherny, Stacey S., Lam, Tai Hing, Thomas, G. Neil, Pan, Wen-Harn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315540/
https://www.ncbi.nlm.nih.gov/pubmed/22479346
http://dx.doi.org/10.1371/journal.pone.0032907