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Oxygen Levels Do Not Determine Radiation Survival of Breast Cancer Stem Cells

For more than a century oxygen has been known to be one of the most powerful radiosensitizers. However, despite decades of preclinical and clinical research aimed at overcoming tumor hypoxia, little clinical progress has been made so far. Ionizing radiation damages DNA through generation of free rad...

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Detalles Bibliográficos
Autores principales: Lagadec, Chann, Dekmezian, Carmen, Bauché, Lucile, Pajonk, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315542/
https://www.ncbi.nlm.nih.gov/pubmed/22479642
http://dx.doi.org/10.1371/journal.pone.0034545