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Effect of Polymorphisms in XPD on Clinical Outcomes of Platinum-Based Chemotherapy for Chinese Non-Small Cell Lung Cancer Patients

PURPOSE: Xeroderma pigmentosum group D (XPD) codes for a DNA helicase involved in nucleotide excision repair that removes platinum-induced DNA damage. Genetic polymorphisms of XPD may affect DNA repair capacity and lead to individual differences in the outcome of patients after chemotherapy. This st...

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Detalles Bibliográficos
Autores principales: Wu, Wenting, Li, Huan, Wang, Huibo, Zhao, Xueying, Gao, Zhiqiang, Qiao, Rong, Zhang, Wei, Qian, Ji, Wang, Jiucun, Chen, Hongyan, Wei, Qingyi, Han, Baohui, Lu, Daru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315552/
https://www.ncbi.nlm.nih.gov/pubmed/22479369
http://dx.doi.org/10.1371/journal.pone.0033200