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Priming with a Recombinant Pantothenate Auxotroph of Mycobacterium bovis BCG and Boosting with MVA Elicits HIV-1 Gag Specific CD8(+) T Cells

A safe and effective HIV vaccine is required to significantly reduce the number of people becoming infected with HIV each year. In this study wild type Mycobacterium bovis BCG Pasteur and an attenuated pantothenate auxotroph strain (BCGΔpanCD) that is safe in SCID mice, have been compared as vaccine...

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Detalles Bibliográficos
Autores principales: Chapman, Rosamund, Shephard, Enid, Stutz, Helen, Douglass, Nicola, Sambandamurthy, Vasan, Garcia, Irene, Ryffel, Bernhard, Jacobs, William, Williamson, Anna-Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315557/
https://www.ncbi.nlm.nih.gov/pubmed/22479338
http://dx.doi.org/10.1371/journal.pone.0032769