Genome Wide Analysis of Acute Myeloid Leukemia Reveal Leukemia Specific Methylome and Subtype Specific Hypomethylation of Repeats

Methylated DNA immunoprecipitation followed by high-throughput sequencing (MeDIP-seq) has the potential to identify changes in DNA methylation important in cancer development. In order to understand the role of epigenetic modulation in the development of acute myeloid leukemia (AML) we have applied...

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Detalles Bibliográficos
Autores principales: Saied, Marwa H., Marzec, Jacek, Khalid, Sabah, Smith, Paul, Down, Thomas A., Rakyan, Vardhman K., Molloy, Gael, Raghavan, Manoj, Debernardi, Silvana, Young, Bryan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315563/
https://www.ncbi.nlm.nih.gov/pubmed/22479372
http://dx.doi.org/10.1371/journal.pone.0033213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315563/
https://www.ncbi.nlm.nih.gov/pubmed/22479372
http://dx.doi.org/10.1371/journal.pone.0033213

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