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Modulation by Endothelin-1 of Spontaneous Activity and Membrane Currents of Atrioventricular Node Myocytes from the Rabbit Heart

BACKGROUND: The atrioventricular node (AVN) is a key component of the cardiac pacemaker-conduction system. Although it is known that receptors for the peptide hormone endothelin-1 (ET-1) are expressed in the AVN, there is very little information available on the modulatory effects of ET-1 on AVN ele...

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Detalles Bibliográficos
Autores principales: Choisy, Stéphanie C., Cheng, Hongwei, Smith, Godfrey L., James, Andrew F., Hancox, Jules C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315568/
https://www.ncbi.nlm.nih.gov/pubmed/22479400
http://dx.doi.org/10.1371/journal.pone.0033448