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Integrated Analyses of microRNAs Demonstrate Their Widespread Influence on Gene Expression in High-Grade Serous Ovarian Carcinoma

BACKGROUND: The Cancer Genome Atlas (TCGA) Network recently comprehensively catalogued the molecular aberrations in 487 high-grade serous ovarian cancers, with much remaining to be elucidated regarding the microRNAs (miRNAs). Here, using TCGA ovarian data, we surveyed the miRNAs, in the context of t...

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Detalles Bibliográficos
Autores principales: Creighton, Chad J., Hernandez-Herrera, Anadulce, Jacobsen, Anders, Levine, Douglas A., Mankoo, Parminder, Schultz, Nikolaus, Du, Ying, Zhang, Yiqun, Larsson, Erik, Sheridan, Robert, Xiao, Weimin, Spellman, Paul T., Getz, Gad, Wheeler, David A., Perou, Charles M., Gibbs, Richard A., Sander, Chris, Hayes, D. Neil, Gunaratne, Preethi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315571/
https://www.ncbi.nlm.nih.gov/pubmed/22479643
http://dx.doi.org/10.1371/journal.pone.0034546