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A Chemical Screen Probing the Relationship between Mitochondrial Content and Cell Size

The cellular content of mitochondria changes dynamically during development and in response to external stimuli, but the underlying mechanisms remain obscure. To systematically identify molecular probes and pathways that control mitochondrial abundance, we developed a high-throughput imaging assay t...

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Detalles Bibliográficos
Autores principales: Kitami, Toshimori, Logan, David J., Negri, Joseph, Hasaka, Thomas, Tolliday, Nicola J., Carpenter, Anne E., Spiegelman, Bruce M., Mootha, Vamsi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315575/
https://www.ncbi.nlm.nih.gov/pubmed/22479437
http://dx.doi.org/10.1371/journal.pone.0033755