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High dimensional and high resolution pulse sequences for backbone resonance assignment of intrinsically disordered proteins

Four novel 5D (HACA(N)CONH, HNCOCACB, (HACA)CON(CA)CONH, (H)NCO(NCA)CONH), and one 6D ((H)NCO(N)CACONH) NMR pulse sequences are proposed. The new experiments employ non-uniform sampling that enables achieving high resolution in indirectly detected dimensions. The experiments facilitate resonance ass...

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Detalles Bibliográficos
Autores principales: Zawadzka-Kazimierczuk, Anna, Koźmiński, Wiktor, Šanderová, Hana, Krásný, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315646/
https://www.ncbi.nlm.nih.gov/pubmed/22350953
http://dx.doi.org/10.1007/s10858-012-9613-x