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Functionally Distinct Subpopulations of CpG-Activated Memory B Cells

During the human B cell (Bc) recall response, rapid cell division results in multiple Bc subpopulations. The TLR-9 agonist CpG oligodeoxynucleotide, combined with cytokines, causes Bc activation and division in vitro and increased CD27 surface expression in a sub-population of Bc. We hypothesized th...

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Detalles Bibliográficos
Autores principales: Henn, Alicia D., Laski, Michael, Yang, Hongmei, Welle, Stephen, Qiu, Xing, Miao, Hongyu, Barry, Christopher T., Wu, Hulin, Zand, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315693/
https://www.ncbi.nlm.nih.gov/pubmed/22468229
http://dx.doi.org/10.1038/srep00345