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Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples

BACKGROUND: The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification of genetic variants affecting quantitative traits within this axis is an attractive goal. However, large sample numbers are a pre-requisite...

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Detalles Bibliográficos
Autores principales: Mullen, Michael P, Creevey, Christopher J, Berry, Donagh P, McCabe, Matt S, Magee, David A, Howard, Dawn J, Killeen, Aideen P, Park, Stephen D, McGettigan, Paul A, Lucy, Matt C, MacHugh, David E, Waters, Sinead M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315736/
https://www.ncbi.nlm.nih.gov/pubmed/22235840
http://dx.doi.org/10.1186/1471-2164-13-16