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Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation
The endoplasmic reticulum (ER) has an elaborate quality control system, which retains misfolded proteins and targets them to ER-associated protein degradation (ERAD). To analyze sorting between ER retention and ER exit to the secretory pathway, we constructed fusion proteins containing both folded c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315801/ https://www.ncbi.nlm.nih.gov/pubmed/22298424 http://dx.doi.org/10.1091/mbc.E11-08-0722 |