Dynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2

Kinesin-5 is an essential mitotic motor. However, how its spatial–temporal distribution is regulated in mitosis remains poorly understood. We expressed localization and affinity purification–tagged Eg5 from a mouse bacterial artificial chromosome (this construct was called mEg5) and found its distri...

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Detalles Bibliográficos
Autores principales: Gable, Alyssa, Qiu, Minhua, Titus, Janel, Balchand, Sai, Ferenz, Nick P., Ma, Nan, Collins, Elizabeth S., Fagerstrom, Carey, Ross, Jennifer L., Yang, Ge, Wadsworth, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315814/
https://www.ncbi.nlm.nih.gov/pubmed/22337772
http://dx.doi.org/10.1091/mbc.E11-09-0820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315814/
https://www.ncbi.nlm.nih.gov/pubmed/22337772
http://dx.doi.org/10.1091/mbc.E11-09-0820

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