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Dynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2
Kinesin-5 is an essential mitotic motor. However, how its spatial–temporal distribution is regulated in mitosis remains poorly understood. We expressed localization and affinity purification–tagged Eg5 from a mouse bacterial artificial chromosome (this construct was called mEg5) and found its distri...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315814/ https://www.ncbi.nlm.nih.gov/pubmed/22337772 http://dx.doi.org/10.1091/mbc.E11-09-0820 |