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MicroRNA Regulation of SIRT1

SIRT1 is an NAD-dependent deacetylase that regulates stress response pathways. By deacetylating transcription factors and co-factors, SIRT1 modulates metabolism, inflammation, hypoxic responses, circadian rhythms, cell survival, and longevity. Since SIRT1 plays a key role in regulating pathways invo...

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Detalles Bibliográficos
Autor principal: Yamakuchi, Munekazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315824/
https://www.ncbi.nlm.nih.gov/pubmed/22479251
http://dx.doi.org/10.3389/fphys.2012.00068