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Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

Cannabidiol is a component of marijuana that does not activate cannabinoid receptors, but moderately inhibits the degradation of the endocannabinoid anandamide. We previously reported that an elevation of anandamide levels in cerebrospinal fluid inversely correlated to psychotic symptoms. Furthermor...

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Detalles Bibliográficos
Autores principales: Leweke, F M, Piomelli, D, Pahlisch, F, Muhl, D, Gerth, C W, Hoyer, C, Klosterkötter, J, Hellmich, M, Koethe, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316151/
https://www.ncbi.nlm.nih.gov/pubmed/22832859
http://dx.doi.org/10.1038/tp.2012.15