Leishmania amazonensis Arginase Compartmentalization in the Glycosome Is Important for Parasite Infectivity

In Leishmania, de novo polyamine synthesis is initiated by the cleavage of L-arginine to urea and L-ornithine by the action of arginase (ARG, E.C. 3.5.3.1). Previous studies in L. major and L. mexicana showed that ARG is essential for in vitro growth in the absence of polyamines and needed for full...

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Detalles Bibliográficos
Autores principales: da Silva, Maria Fernanda Laranjeira, Zampieri, Ricardo Andrade, Muxel, Sandra M., Beverley, Stephen M., Floeter-Winter, Lucile M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316525/
https://www.ncbi.nlm.nih.gov/pubmed/22479507
http://dx.doi.org/10.1371/journal.pone.0034022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316525/
https://www.ncbi.nlm.nih.gov/pubmed/22479507
http://dx.doi.org/10.1371/journal.pone.0034022

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