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Leishmania amazonensis Arginase Compartmentalization in the Glycosome Is Important for Parasite Infectivity
In Leishmania, de novo polyamine synthesis is initiated by the cleavage of L-arginine to urea and L-ornithine by the action of arginase (ARG, E.C. 3.5.3.1). Previous studies in L. major and L. mexicana showed that ARG is essential for in vitro growth in the absence of polyamines and needed for full...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316525/ https://www.ncbi.nlm.nih.gov/pubmed/22479507 http://dx.doi.org/10.1371/journal.pone.0034022 |