Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice

Advancement of biomedical applications of carbonaceous nanomaterials is hampered by their biopersistence and pro-inflammatory action in vivo. Here, we used myeloperoxidase knockout B6.129X1-MPO (MPO k/o) mice and showed that oxidation and clearance of single walled carbon nanotubes (SWCNT) from the...

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Detalles Bibliográficos
Autores principales: Shvedova, Anna A., Kapralov, Alexandr A., Feng, Wei Hong, Kisin, Elena R., Murray, Ashley R., Mercer, Robert R., St. Croix, Claudette M., Lang, Megan A., Watkins, Simon C., Konduru, Nagarjun V., Allen, Brett L., Conroy, Jennifer, Kotchey, Gregg P., Mohamed, Bashir M., Meade, Aidan D., Volkov, Yuri, Star, Alexander, Fadeel, Bengt, Kagan, Valerian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316527/
https://www.ncbi.nlm.nih.gov/pubmed/22479306
http://dx.doi.org/10.1371/journal.pone.0030923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316527/
https://www.ncbi.nlm.nih.gov/pubmed/22479306
http://dx.doi.org/10.1371/journal.pone.0030923

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