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Protein Phosphatase 1 Dephosphorylates Profilin-1 at Ser-137
Profilin-1 (PFN1) plays an important role in the control of actin dynamics, and could represent an important therapeutic target in several diseases. We previously identified PFN1 as a huntingtin aggregation inhibitor, and others have implicated it as a tumor-suppressor. Rho-associated kinase (ROCK)...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316545/ https://www.ncbi.nlm.nih.gov/pubmed/22479341 http://dx.doi.org/10.1371/journal.pone.0032802 |