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MicroRNA let-7c Is Downregulated in Prostate Cancer and Suppresses Prostate Cancer Growth

PURPOSE: Prostate cancer (PCa) is characterized by deregulated expression of several tumor suppressor or oncogenic miRNAs. The objective of this study was the identification and characterization of miR-let-7c as a potential tumor suppressor in PCa. EXPERIMENTAL DESIGN: Levels of expression of miR-le...

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Detalles Bibliográficos
Autores principales: Nadiminty, Nagalakshmi, Tummala, Ramakumar, Lou, Wei, Zhu, Yezi, Shi, Xu-Bao, Zou, June X., Chen, Hongwu, Zhang, Jin, Chen, Xinbin, Luo, Jun, deVere White, Ralph W., Kung, Hsing-Jien, Evans, Christopher P., Gao, Allen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316551/
https://www.ncbi.nlm.nih.gov/pubmed/22479342
http://dx.doi.org/10.1371/journal.pone.0032832