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Knock-Down of Core Proteins Regulating MicroRNA Biogenesis Has No Effect on Sensitivity of Lung Cancer Cells to Ionizing Radiation

Recent studies underline the important role of microRNAs (miRNA) in the development of lung cancer. The main regulators of miRNA biogenesis are the ribonucleases Drosha, Dicer and Ago2. Here the role of core proteins of miRNA biogenesis machinery in the response of human non-small and small cell lun...

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Detalles Bibliográficos
Autores principales: Surova, Olga, Akbar, Nadeem Shahzad, Zhivotovsky, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316564/
https://www.ncbi.nlm.nih.gov/pubmed/22479364
http://dx.doi.org/10.1371/journal.pone.0033134