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Genes Are Often Sheltered from the Global Histone Hyperacetylation Induced by HDAC Inhibitors
Histone deacetylase inhibitors (HDACi) are increasingly used as therapeutic agents, but the mechanisms by which they alter cell behaviour remain unclear. Here we use microarray expression analysis to show that only a small proportion of genes (∼9%) have altered transcript levels after treating HL60...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316569/ https://www.ncbi.nlm.nih.gov/pubmed/22479401 http://dx.doi.org/10.1371/journal.pone.0033453 |