The Tyrosine Kinase c-Src Directly Mediates Growth Factor-Induced Notch-1 and Furin Interaction and Notch-1 Activation in Pancreatic Cancer Cells

The proteolytic activity of Furin responsible for processing full length Notch-1 (p300) plays a critical role in Notch signaling. The amplitude and duration of Notch activity can be regulated at various points in the pathway, but there has been no report regarding regulation of the Notch-1-Furin int...

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Detalles Bibliográficos
Autores principales: Ma, Yong-Chao, Shi, Chong, Zhang, Yao-Nan, Wang, Lan-Ge, Liu, Hao, Jia, Hong-Ti, Zhang, Yu-Xiang, Sarkar, Fazlul H., Wang, Ze-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316571/
https://www.ncbi.nlm.nih.gov/pubmed/22479394
http://dx.doi.org/10.1371/journal.pone.0033414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316571/
https://www.ncbi.nlm.nih.gov/pubmed/22479394
http://dx.doi.org/10.1371/journal.pone.0033414

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