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Characterization of the Interaction of Full-Length HIV-1 Vif Protein with its Key Regulator CBFβ and CRL5 E3 Ubiquitin Ligase Components

Human immunodeficiency virus-1 (HIV-1) viral infectivity factor (Vif) is essential for viral replication because of its ability to eliminate the host's antiviral response to HIV-1 that is mediated by the APOBEC3 family of cellular cytidine deaminases. Vif targets these proteins, including APOBE...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaohong, Evans, Sean L., Han, Xue, Liu, Yayan, Yu, Xiao-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316577/
https://www.ncbi.nlm.nih.gov/pubmed/22479405
http://dx.doi.org/10.1371/journal.pone.0033495