Temporal Patterns of Nucleotide Misincorporations and DNA Fragmentation in Ancient DNA

DNA that survives in museum specimens, bones and other tissues recovered by archaeologists is invariably fragmented and chemically modified. The extent to which such modifications accumulate over time is largely unknown but could potentially be used to differentiate between endogenous old DNA and pr...

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Detalles Bibliográficos
Autores principales: Sawyer, Susanna, Krause, Johannes, Guschanski, Katerina, Savolainen, Vincent, Pääbo, Svante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316601/
https://www.ncbi.nlm.nih.gov/pubmed/22479540
http://dx.doi.org/10.1371/journal.pone.0034131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316601/
https://www.ncbi.nlm.nih.gov/pubmed/22479540
http://dx.doi.org/10.1371/journal.pone.0034131

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