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Temporal Patterns of Nucleotide Misincorporations and DNA Fragmentation in Ancient DNA
DNA that survives in museum specimens, bones and other tissues recovered by archaeologists is invariably fragmented and chemically modified. The extent to which such modifications accumulate over time is largely unknown but could potentially be used to differentiate between endogenous old DNA and pr...
Autores principales: | Sawyer, Susanna, Krause, Johannes, Guschanski, Katerina, Savolainen, Vincent, Pääbo, Svante |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316601/ https://www.ncbi.nlm.nih.gov/pubmed/22479540 http://dx.doi.org/10.1371/journal.pone.0034131 |
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