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Increased Fibrosis and Interstitial Fluid Pressure in Two Different Types of Syngeneic Murine Carcinoma Grown in Integrin β3-Subunit Deficient Mice

Stroma properties affect carcinoma physiology and direct malignant cell development. Here we present data showing that α(V)β(3) expressed by stromal cells is involved in the control of interstitial fluid pressure (IFP), extracellular volume (ECV) and collagen scaffold architecture in experimental mu...

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Detalles Bibliográficos
Autores principales: Friman, Tomas, Gustafsson, Renata, Stuhr, Linda B., Chidiac, Jean, Heldin, Nils-Erik, Reed, Rolf K., Oldberg, Åke, Rubin, Kristofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316610/
https://www.ncbi.nlm.nih.gov/pubmed/22479530
http://dx.doi.org/10.1371/journal.pone.0034082