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Increased Fibrosis and Interstitial Fluid Pressure in Two Different Types of Syngeneic Murine Carcinoma Grown in Integrin β3-Subunit Deficient Mice
Stroma properties affect carcinoma physiology and direct malignant cell development. Here we present data showing that α(V)β(3) expressed by stromal cells is involved in the control of interstitial fluid pressure (IFP), extracellular volume (ECV) and collagen scaffold architecture in experimental mu...
Autores principales: | Friman, Tomas, Gustafsson, Renata, Stuhr, Linda B., Chidiac, Jean, Heldin, Nils-Erik, Reed, Rolf K., Oldberg, Åke, Rubin, Kristofer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316610/ https://www.ncbi.nlm.nih.gov/pubmed/22479530 http://dx.doi.org/10.1371/journal.pone.0034082 |
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