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Molecular Dynamics Analysis of Apolipoprotein-D - Lipid Hydroperoxide Interactions: Mechanism for Selective Oxidation of Met-93

BACKGROUND: Recent studies suggest reduction of radical-propagating fatty acid hydroperoxides to inert hydroxides by interaction with apolipoprotein-D (apoD) Met93 may represent an antioxidant function for apoD. The nature and structural consequences of this selective interaction are unknown. METHOD...

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Detalles Bibliográficos
Autores principales: Oakley, Aaron J., Bhatia, Surabhi, Ecroyd, Heath, Garner, Brett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316614/
https://www.ncbi.nlm.nih.gov/pubmed/22479522
http://dx.doi.org/10.1371/journal.pone.0034057