A Knockout of the Tsg101 Gene Leads to Decreased Expression of ErbB Receptor Tyrosine Kinases and Induction of Autophagy Prior to Cell Death

The Tumor Susceptibility Gene 101 (Tsg101) encodes a multi-domain protein that mediates a variety of molecular and biological processes including the trafficking and lysosomal degradation of cell surface receptors. Conventional and conditional knockout models have demonstrated an essential requireme...

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Detalles Bibliográficos
Autores principales: Morris, Chantey R., Stanton, Marissa J., Manthey, Karoline C., Oh, Keon Bong, Wagner, Kay-Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316634/
https://www.ncbi.nlm.nih.gov/pubmed/22479596
http://dx.doi.org/10.1371/journal.pone.0034308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316634/
https://www.ncbi.nlm.nih.gov/pubmed/22479596
http://dx.doi.org/10.1371/journal.pone.0034308

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